Radiologically isolated syndrome: an uncommon finding at a university clinic in a high-prevalence region for multiple sclerosis

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Radiologically isolated syndrome: an uncommon finding at a university clinic in a high-prevalence region for multiple sclerosis

OBJECTIVE The improved availability of MRI in medicine has led to an increase in incidental findings. Unexpected brain MRI findings suggestive of multiple sclerosis (MS) without typical symptoms of MS were recently defined as radiologically isolated syndrome (RIS). The prevalence of RIS is uncertain. The aim of this study was to determine the prevalence of RIS at a university hospital in a regi...

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The radiologically isolated syndrome dilemma: just an incidental radiological finding or presymptomatic multiple sclerosis?

MULTIPLE SCLEROSIS MSJ JOURNAL With the increasing use of brain magnetic resonance imaging (MRI) by clinicians, researchers and even companies that carry out health checkups the finding of asymptomatic intracranial abnormalities of potential clinical significance has risen tremendously. 1 In a recent meta-analysis, the prevalence of neoplastic and non-neoplastic incidental findings on brain MRI...

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Conversion from Radiologically Isolated Syndrome to Multiple Sclerosis

BACKGROUND The aim of this study was to estimate the conversion rate from radiologically isolated syndrome (RIS) to definite multiple sclerosis (MS). METHODS During a mean (standard deviation [SD]) follow-up period of 17.4 (5.4) (range 8-29) months, 25 subjects with RIS and without neurological symptom aged 22-45 year from a single-center have been examined for the occurrence of definite MS. ...

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conversion from radiologically isolated syndrome to multiple sclerosis

background: the aim of this study was to estimate the conversion rate from radiologically isolated syndrome (ris) to definite multiple sclerosis (ms). methods: during a mean (standard deviation [sd]) follow-up period of 17.4 (5.4) (range 8-29) months, 25 subjects with ris and without neurological symptom aged 22-45 year from a single-center have been examined for the occurrence of definite ms. ...

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How much radiologically isolated syndrome suggestive of multiple sclerosis is multiple sclerosis?

In spite of the progress in Neuroimmunology, a specific biomarker for the diagnosis of multiple sclerosis (MS) remains to be defined. Meanwhile, as growing enthusiasm has been associated with the development of new therapeutic options and the recent evidence that the disease-modifying agents may be more beneficial for MS patients if initiated as early as possible following disease onset1, inves...

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ژورنال

عنوان ژورنال: BMJ Open

سال: 2013

ISSN: 2044-6055,2044-6055

DOI: 10.1136/bmjopen-2013-003531